First take an egg cell. Take away its nucleus. Insert the skin cell nucleus into the egg cell. Induce it to grow. At the blastocyst stage, take out the stem cell mass. Grow this stem cell in culture media. Different tissue can be grown by changing its parameter such as the temperature, media nutrient and adding other signals.
In the newer cloning technique, the nucleus of the egg is not removed.
For knee joint arthritis and other body parts and joint pain treatment without drugs.